From 1991 to 1998, Dr. Chen was a research physician at the Shenzhen Institute of Integrative Chinese and Western Medicine, Shenzhen Red Cross Hospital (Shenzhen 2nd People’s Hospital). In 1998, Dr. Chen decided to change his fields of research from clinically-orientated studies to fundamental laboratory research in immunology using his strong background of alternative medicines. Dr. Chen started his Post Doctoral training at the School of Pharmacy and Biomedical Sciences, University of Portsmouth, UK. In April of 1999, Dr. Chen joined the Laboratory of Molecular Immunoregulation, National Cancer Institute (NCI)-Frederick, NIH, USA, as a Visiting Fellow. In 2001, Dr. Chen became a Scientist II in the Laboratory of Molecular Immunoregulation, Basic Science Program, SAIC-Frederick, Inc., NCI-Frederick. From 2011 to 2014, he was a Senior Scientist in the same group. In October of 2014, He joined the University of Macau. Now he is a Professor of Biomedical Sciences at State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China